digoxin
Differences
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| digoxin [2026/06/27 23:34] – [slow digitalisation for Mx of AF or cardiac failure in adults] wh | digoxin [2026/06/28 00:31] (current) – [rapid digitalisation for Mx of RAF in adults] wh | ||
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| ====rapid digitalisation for Mx of RAF in adults==== | ====rapid digitalisation for Mx of RAF in adults==== | ||
| ===usual dosing=== | ===usual dosing=== | ||
| - | *aim for max 0.75-1.5mg ((10 to 12 mcg/kg lean body weight) total load dose in 1st 24hrs | + | |
| *load dose should be reduced to total 0.75mg if patient has a condition which makes them sensitive to digoxin such as: | *load dose should be reduced to total 0.75mg if patient has a condition which makes them sensitive to digoxin such as: | ||
| * [[hypokalaemia]] | * [[hypokalaemia]] | ||
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| *load dose should also be halved in those with chronic renal impairment and digoxin Rx is generally avoided in those with ESRF or on dialysis | *load dose should also be halved in those with chronic renal impairment and digoxin Rx is generally avoided in those with ESRF or on dialysis | ||
| *load dose should also be halved in those who weigh < 45kg | *load dose should also be halved in those who weigh < 45kg | ||
| - | *IV adults 0.5mg (halve dose in impaired renal function) diluted to 10mL normal saline over 10 minutes every 6hrs for total two-three doses up to total load dose of 1-1.5mg in 1st 24 hours, or, | + | *IV adults 0.5mg (halve dose in impaired renal function) diluted to 10mL normal saline over 10 minutes every 6hrs for total two-three doses up to total load dose as above, or, |
| *oral 0.25-0.5mg every 6hrs | *oral 0.25-0.5mg every 6hrs | ||
digoxin.txt · Last modified: 2026/06/28 00:31 by wh