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dvt [2026/09/09 23:33] – [Unprovoked "spontaneous" DVTs (40%)] gary1dvt [2026/11/12 10:49] (current) – [Unprovoked "spontaneous" DVTs (40%)] gary1
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   *hormonal therapy especially oestrogens   *hormonal therapy especially oestrogens
   *smoking   *smoking
 +  *raised [[BNP]] may be a predisposing factor
 +    * BNP can bind to natriuretic peptide receptor-A (NPRA) on platelets significantly increasing intracellular cGMP levels and enhanced platelet aggregation, granule secretion, spreading, and clot retraction in vitro(([[https://ashpublications.org/blood/article/doi/10.1182/blood.2026035455/571101/BNP-Promotes-Platelet-Activation-and-Thrombosis|2026: BNP Promotes Platelet Activation and Thrombosis via its Receptor NPRA: A Paradigm Shift from Biomarker to Effector]]))
   ***hereditary [[thrombophilia]]**   ***hereditary [[thrombophilia]]**
   *pelvic pressure on pelvic veins eg. pelvic masses   *pelvic pressure on pelvic veins eg. pelvic masses
dvt.txt · Last modified: by gary1

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