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--- ebv [2026/08/25 11:10] – [adolescent infectious mononucleosis] gary1
+++ ebv [2026/08/25 11:13] (current) – [adolescent infectious mononucleosis] gary1
@@ Line 50: / Line 50: @@
       *EBV  may account for ~5% of children admitted with encephalitis(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC4322508/|2015: Epstein-Barr Virus Encephalitis: A Case Report]]))(([[https://radiopaedia.org/articles/epstein-barr-virus-encephalitis-2]]))
       *EBV has a tropism for the deep nuclei, neuroimaging can show characteristic multiple foci of T2-weighted or FLAIR hyper intensity in the hemispheric cortex, brain stem, bilateral thalami, and basal ganglia(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC4322508/|2015: Epstein-Barr Virus Encephalitis: A Case Report]])), although one study suggests MRI is only abnormal in 71% of paediatric patients with EBV encephalitis (([[https://radiopaedia.org/articles/epstein-barr-virus-encephalitis-2]]))
+      *compared to other herpes virus-associated encephalitis, EBV encephalitis is characterized by a higher degree of meningeal involvement, elevated CSF protein levels, lower glucose levels, and a reduced T-lymphocyte count in peripheral blood(([[https://link.springer.com/article/10.1186/s12985-025-02768-w|2025: Clinical features and risk factors for Epstein-Barr virus-associated encephalitis: a retrospective cohort study]]))
       *transverse myelitis
       *acute cerebellar ataxia