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--- git_microbiome [2026/07/09 00:57] – [Ageing] gary1
+++ git_microbiome [2026/10/08 00:48] (current) – [Normal gut microbiome] gary1
@@ Line 54: / Line 54: @@
       * //Methanobrevibacter intestini// produces methane from hydrogen and CO<sub>2</sub> as well as high levels of succinic acid—a compound linked to inflammatory processes
       * GRAZ-2 variant of //Methanobrevibacter smithii// produces formic acid, which may impact the metabolism of neighboring gut microbes ((Viktoria Weinberger et al., "Expanding the cultivable human archaeome: Methanobrevibacter intestini sp. nov. and strain Methanobrevibacter smithii 'GRAZ-2' from human faeces," International Journal of Systematic and Evolutionary Microbiology (2025) ))
+  *it appears that when humans initially migrated from Africa in prehistoric times, they took most of the GIT microbiome with them however many of these original microbiome organisms have been replaced in industrialized populations(([[https://www.nature.com/articles/s41586-026-11106-1|2026: Prehistoric global migration of vanishing gut microbes with humans]]))
   *long-term diet is strongly associated with the gut microbiome composition
     * those who eat plenty of protein and animal fats have predominantly Bacteroides bacteria, while for those who consume more carbohydrates the Prevotella species dominate(([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368382|Science. 2011; 334 (6052): 105–108. ]]))