hsv
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| hsv [2025/10/18 10:16] – [Pathophysiologic aspects] gary1 | hsv [2025/10/18 10:16] (current) – [Pathophysiologic aspects] gary1 | ||
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| ***HSV is the prime cause of [[erythema_multiforme]]** which is a delayed HS reaction to a HSV outbreak 7-10 days earlier which may be asymptomatic | ***HSV is the prime cause of [[erythema_multiforme]]** which is a delayed HS reaction to a HSV outbreak 7-10 days earlier which may be asymptomatic | ||
| - | =====Pathophysiologic aspects===== | + | =====Pathophysiologic |
| *HSV1 virus causes over-expression of host cell peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) enzyme which then allows it to more readily escape from the host cell nucleus and replicate and infect other cells | *HSV1 virus causes over-expression of host cell peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) enzyme which then allows it to more readily escape from the host cell nucleus and replicate and infect other cells | ||
| * in 2025, studies into Pin1 inhibitors showed that they can trap HSV-1 in the host cell nucleus and this could potentially be used as a therapeutic to reduce infectivity and potentially, | * in 2025, studies into Pin1 inhibitors showed that they can trap HSV-1 in the host cell nucleus and this could potentially be used as a therapeutic to reduce infectivity and potentially, | ||
hsv.txt · Last modified: 2025/10/18 10:16 by gary1