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il-6 [2026/08/31 10:50] – [IL-6 blocking agents] gary1il-6 [2026/08/31 10:51] (current) – [IL-6 blocking agents] gary1
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   * **pacibekitug**   * **pacibekitug**
     * long acting anti-interleukin-6 monoclonal antibody     * long acting anti-interleukin-6 monoclonal antibody
-    * in the TRANQUILITY phase 2 study, it reduced 180 day hsCRP levels by 76-89% compared with control and was generally well tolerated(([[https://www.news-medical.net/news/20260829/Investigational-anti-interleukin-6-monoclonal-antibody-achieves-durable-inflammatory-biomarker-reductions.aspx]]))+    * in the TRANQUILITY phase 2 study, it reduced 180 day hsCRP levels by 76-89% compared with 7% increase in the control group and was generally well tolerated(([[https://www.news-medical.net/news/20260829/Investigational-anti-interleukin-6-monoclonal-antibody-achieves-durable-inflammatory-biomarker-reductions.aspx]]))
   * **baricitinib**   * **baricitinib**
     * JAK1/JAK2 inhibitor used to Rx [[psoriasis]]     * JAK1/JAK2 inhibitor used to Rx [[psoriasis]]
il-6.txt · Last modified: 2026/08/31 10:51 by gary1

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