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melanoma [2026/05/10 19:54] – [familial factors] whmelanoma [2026/05/10 19:55] (current) – [familial factors] wh
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       * people who have olive and darker skin and who carry one or more variations of this gene have a higher than average risk for melanoma.       * people who have olive and darker skin and who carry one or more variations of this gene have a higher than average risk for melanoma.
     * TYR, TYRP1, and ASIP genes     * TYR, TYRP1, and ASIP genes
-    * 0.5% have AD POT1 mutation and this is associated also with lymphomas (([[https://ashpublications.org/blood/article/147/19/2226/566170/Lymphoid-malignancy-and-clonality-in-the-POT1|2026: Lymphoid malignancy and clonality in the POT1-mediated long telomere syndrome ]]))+    * 0.5% have AD POT1 mutation and this is associated also with lymphomas - accounts for 2.4-4% of familial melanoma cases (([[https://ashpublications.org/blood/article/147/19/2226/566170/Lymphoid-malignancy-and-clonality-in-the-POT1|2026: Lymphoid malignancy and clonality in the POT1-mediated long telomere syndrome ]]))
  
 ====gene mutations==== ====gene mutations====
melanoma.txt · Last modified: 2026/05/10 19:55 by wh · Currently locked by: wh

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