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| memory [2026/01/20 23:47] – [infantile memory] gary1 | memory [2026/01/20 23:47] (current) – [infantile amnesia] gary1 |
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| =====infantile amnesia===== | =====infantile amnesia===== |
| *most people (and other "altricial" mammals, which are those that are born in a helpless, vulnerable state and are completely reliant on their caregiver) remember nothing from our early years of life before age 4-5 yrs, despite having so many novel experiences during these formative years. | *most people (and other "altricial" mammals, which are those that are born in a helpless, vulnerable state and are completely reliant on their caregiver) remember nothing from their early years of life (eg. before age 4-5 yrs), despite having so many novel experiences during these formative years. |
| *"precocial" mammals such as guinea pigs, born in a more advanced state of maturation with greater independence, do not display infantile amnesia | *"precocial" mammals such as guinea pigs, born in a more advanced state of maturation with greater independence, do not display infantile amnesia |
| *it appears this loss of early memory is managed by microglia.(([[https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003538|2026: Microglial activity during postnatal development is required for infantile amnesia in mice]])) | *it appears this loss of early memory is managed by microglia.(([[https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003538|2026: Microglial activity during postnatal development is required for infantile amnesia in mice]])) |
| *it seems that the brain is filing away the neuronal units that store memory, the engrams, for later use and that microglia seem to be functioning in the brain to help organise how engrams are stored and expressed across the lifetime(([[https://www.news-medical.net/news/20260120/Blocking-microglia-can-prevent-infantile-amnesia.aspx]])) | *it seems that the brain is filing away the neuronal units that store memory, the engrams, for later use and that microglia seem to be functioning in the brain to help organise how engrams are stored and expressed across the lifetime(([[https://www.news-medical.net/news/20260120/Blocking-microglia-can-prevent-infantile-amnesia.aspx]])) |
