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migraine [2026/09/15 08:36] – [migraine triggers:] gary1migraine [2026/09/15 08:37] (current) – [migraine triggers:] gary1
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       *phenylethylamine-containing (eg. chocolate)       *phenylethylamine-containing (eg. chocolate)
       *1-octopamine (eg. citrus)       *1-octopamine (eg. citrus)
-      *[[nitrosamines|nitrates and nitrites]] (eg. processed meats)+      *[[nitrosamines|nitrates and nitrites]] (eg. certain vegetables)
         *whilst the immediate headache of topical nitrates such as GTN is probably just NO induced vasodilatation, the delayed onset headache 3-5 hours after topical nitrates produces a migraine-like headache in those at risk and is thought to be due to NO induced increase release of CGRP         *whilst the immediate headache of topical nitrates such as GTN is probably just NO induced vasodilatation, the delayed onset headache 3-5 hours after topical nitrates produces a migraine-like headache in those at risk and is thought to be due to NO induced increase release of CGRP
         ***migraine sufferers appear to have a significantly higher abundance of nitrate-reducing bacteria in their mouths and guts than non-sufferers and thus theoretically could produce more NO from the high salivary nitrate levels**(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC5080405/|2016: Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort]]))         ***migraine sufferers appear to have a significantly higher abundance of nitrate-reducing bacteria in their mouths and guts than non-sufferers and thus theoretically could produce more NO from the high salivary nitrate levels**(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC5080405/|2016: Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort]]))
migraine.txt · Last modified: 2026/09/15 08:37 by gary1

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