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migraine [2026/07/16 12:13] – [pharmacology of antimigraine drugs:] gary1migraine [2026/07/16 12:58] (current) – [pathophysiology] gary1
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   *see also:   *see also:
     *[[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444225/|Ann Indian Acad Neurol. 2012 Aug; 15(Suppl 1): S15–S22. Pathophysiology of migraine]]     *[[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444225/|Ann Indian Acad Neurol. 2012 Aug; 15(Suppl 1): S15–S22. Pathophysiology of migraine]]
-  *it seems likely that the trigeminovascular system and its cranial autonomic reflex connections, the trigeminal–autonomic reflex, act as a feed-forward system to facilitate the acute attack, the fundamental problem in migraine is in the brain due to inherited channelopathies and is no longer considered to be caused by cerebral vasodilatation.+  *it seems likely that the trigeminovascular system and its cranial autonomic reflex connections, the trigeminal–autonomic reflex, act as a feed-forward system to facilitate the acute attack, the fundamental problem in migraine is in the brain possibly due to inherited channelopathies and is no longer considered to be caused by cerebral vasodilatation.
   *the group of neurons from the superficial laminae of trigeminal nucleus caudalis and C1/2 dorsal horns can be regarded functionally as the “trigeminocervical” complex and can explain the occipital headache component of migraine   *the group of neurons from the superficial laminae of trigeminal nucleus caudalis and C1/2 dorsal horns can be regarded functionally as the “trigeminocervical” complex and can explain the occipital headache component of migraine
   *the large cerebral vessels, pial vessels, large venous sinuses and dura mater is surrounded by a plexus of largely unmyelinated fibers that arise from the ophthalmic division of the trigeminal ganglion and in the posterior fossa from the upper cervical dorsal roots   *the large cerebral vessels, pial vessels, large venous sinuses and dura mater is surrounded by a plexus of largely unmyelinated fibers that arise from the ophthalmic division of the trigeminal ganglion and in the posterior fossa from the upper cervical dorsal roots
migraine.txt · Last modified: 2026/07/16 12:58 by gary1

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