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mitochondria [2026/10/12 13:35] – [Overview of roles of mitochondria] gary1mitochondria [2026/10/12 13:37] (current) – [Overview of roles of mitochondria] gary1
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       * mitochondria actively regulate, sustain, and feedback into the body's 24-hour cycle       * mitochondria actively regulate, sustain, and feedback into the body's 24-hour cycle
         * mitochondria are deeply involved in the synthesis and metabolism of major circadian hormones (eg. cortisol)         * mitochondria are deeply involved in the synthesis and metabolism of major circadian hormones (eg. cortisol)
-          * NB. whilst 95% of the body production of melatonin is via local mitochondria, this is not circadian but produced as needed by the mitochondria - circadian melatonin is produced by the pineal gland and constitutes the remaining 5% of total body melatonin synthesis+          * NB. whilst 95% of the body production of melatonin is via local mitochondria, this is not circadian but produced as needed by the mitochondria - circadian melatonin is produced by the pineal gland cytoplasm via AANAT enzyme and constitutes the remaining 5% of total body melatonin synthesis
         * when you wake up and encounter daylight, mitochondria in your cells fuse into long, interconnected networks. This structural change makes them highly efficient at generating the surging energy (ATP) needed for your daytime cognitive and physical activities, in addition, mitochondria ramp up the production of enzymes required to burn carbohydrates and lipids, preparing the body for breakfast and daytime energy consumption         * when you wake up and encounter daylight, mitochondria in your cells fuse into long, interconnected networks. This structural change makes them highly efficient at generating the surging energy (ATP) needed for your daytime cognitive and physical activities, in addition, mitochondria ramp up the production of enzymes required to burn carbohydrates and lipids, preparing the body for breakfast and daytime energy consumption
         * as you stay awake, the continuous burden of aerobic metabolism stresses the mitochondria and they begin to fragment into smaller pieces (fission).          * as you stay awake, the continuous burden of aerobic metabolism stresses the mitochondria and they begin to fragment into smaller pieces (fission). 
mitochondria.txt · Last modified: 2026/10/12 13:37 by gary1

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