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--- steatohepatitis [2026/09/30 11:53] – [non-alcoholic steatohepatitis (NASH)] gary1
+++ steatohepatitis [2026/09/30 11:56] (current) – [non-alcoholic steatohepatitis (NASH) or non-alcoholic fatty liver disease (NAFLD)] gary1
@@ Line 26: / Line 26: @@
   *a lean body mass form "lean MALSD/MASH" is common in Asians with normal BMI
     * reduced steatosis but significant inflammation and fibrosis
-    * this may be partly due to high salt intake causing HS2WDF increased urea cycle flux, EIF5AH, and mitochondrial biogenesis (([[https://www.sciencedirect.com/science/article/pii/S2212877826001018?via%3Dihub|2026: High salt supplementation of a MASH-inducing diet causes lean MASH phenotype with increased hepatic urea cycle activity and EIF5A hypusination]]))
+    * prevalence of lean MASLD/MASH ranges from 1.94% to 13.11%
+    * lower prevalence of diabetes while paradoxically having higher risk of all-cause mortality
+    * this may be partly due to high salt and high fructose intake causing increased urea cycle flux, EIF5AH, and mitochondrial biogenesis (([[https://www.sciencedirect.com/science/article/pii/S2212877826001018?via%3Dihub|2026: High salt supplementation of a MASH-inducing diet causes lean MASH phenotype with increased hepatic urea cycle activity and EIF5A hypusination]]))
   *risk factors:
     *high fructose diet