Differences

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--- vasculitis [2026/06/21 06:45] – [small vessel vasculitis] wh
+++ vasculitis [2026/06/21 06:46] (current) – [small vessel vasculitis] wh
@@ Line 36: / Line 36: @@
 =====small vessel vasculitis=====
   *[[HSP]]
-    *IgA immune deposition in small vessels mainly in children but can occur in adults and when it does is often more severe with greater renal damage (30% develop renal impairment, usually within 2 months of onset, but can be up to 6 months, however, steroids do not appear to reduce the risk)(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC3125277/|2011: The clinical implications of adult-onset henoch-schonelin purpura]])) requiring more close monitoring +/- colchicine for severe skin lesions, +/- steroids for severe GIT involvement or nephrotic range proteinuria / rapid progressive GN.
+    *palpable purpura in dependent part of body, abdominal pain (which may be associated with GI hemorrhage or intussusception in children), arthritis, and evidence of [[GN]]
-    *palpable purpura in dependent part of body, abdominal pain (which may be associated with GI hemorrhage or intussusception), arthritis, and evidence of [[GN]]
+    *IgA immune deposition in small vessels
+    *90% of cases occur in children but can occur in adults and when it does is often more severe with greater renal damage (30% develop renal impairment, usually within 2 months of onset, but can be up to 6 months, however, steroids do not appear to reduce the risk)(([[https://pmc.ncbi.nlm.nih.gov/articles/PMC3125277/|2011: The clinical implications of adult-onset henoch-schonelin purpura]])) requiring more close monitoring +/- colchicine for severe skin lesions, +/- steroids for severe GIT involvement or nephrotic range proteinuria / rapid progressive GN.
     *~60% of adults have elevated serum IgA levels
   *hypersensitivity vasculitis