B-type natriuretic peptide (BNP)

see also:

• troponin
• cardiac markers (troponin)
• congestive cardiac failure

• B-type natriuretic peptide (BNP) is a cardiac-derived vasodilator and a biomarker for heart failure
• elevated BNP and its cleavage product N-terminal proBNP (NT-proBNP) also predict adverse outcomes in acute coronary syndromes and other cardiovascular diseases¹⁾

• BNP can bind to natriuretic peptide receptor-A (NPRA) on platelets significantly increasing intracellular cGMP levels and enhanced platelet aggregation, granule secretion, spreading, and clot retraction in vitro²⁾