dual orexin-A and orexin-B antagonists (Doras)

see also:

• orexin
• sleep

• dual orexin-A and orexin-B antagonists (Doras) block both orexin-A and orexin-B receptors in the brain
• they are being trialled to help Mx narcolepsy as they are expected to promote sleep with fewer side effects than GABA-based hypnotics