Table of Contents
introduction
physiology
secretion increased by
secretion inhibited by
C/I
adverse effects
glucagon
see also:
hormones
insulin
introduction
a peptide hormone, produced by alpha cells of the pancreas, that raises blood glucose levels by stimulating gluconeogenesis and glycogenolysis in the liver, and turns off glycolysis
it can be also given parenterally to Rx
hypoglycaemia
,
beta adrenergic blocker overdose
and impacted food bolus in oesophagus
it can also be given to patients on
beta adrenergic blockers
who develop
anaphylaxis
which is resistant to
adrenaline / epinephrine
Rx.
physiology
secretion increased by
hypoglycaemia
adrenaline
arginine
alanine
acetylcholine
cholecystokinin (CCK)
secretion inhibited by
somatostatin
insulin
(via GABA)
increased free fatty acids or keto acids in the blood
increased urea production
C/I
phaechromocytoma
insulinoma
adverse effects
headache
nausea
hyperglycaemia
hypertension