Table of Contents

acute unilateral headache

see also:

introduction

acute severe retro-orbital pain

patterns of recurrent unilateral headaches

feature migraine cluster headache hemicrania
prevalence common ~25% adult females uncommon <1% adults v. uncommon < 0.01% adults?
gender females 2-3:1 males 2:1 females 2-3:1
risk factors pregnancy, hormonal Rx, genetic heavy smokers/alcoholism
precipitants hormones, menses, stress, smells, dehydration, flickering lights, TV, red wine, beer, some foods, lack of sleep REM sleep, sex, hot weather, TV, histamine, alcohol, nitrates pressure on upper Cx spine, neck movement
character usually throbbing sudden, lancinating retro-orbital throbbing
behaviour during attack quiet, dark room agitated, walking around sit or curl up in bed
associated features nausea, vomit, photophobia, phonophobia +/- aura ipsil. lacrimation, nasal congestion, eyelid oedema, miosis ipsil. lacrimation, nasal congestion, red eyes
duration hours-days 5min-3hrs 3-45 min (but hemicrania continua can last weeks)
specific Rx triptans, iv chlorpromazine 100% oxygen indomethacin 25-50mg tds
preventors 50% effective eg. betablockers, valproate calcium channel blockers low dose indomethacin 25-50mg tds