Table of Contents
Introduction
oral stool softeners
oral bulking agents
oral osmotic agents
oral stimulant laxatives
laxatives
see also:
constipation
Introduction
see under Mx of
constipation
oral stool softeners
docusate
240mg (2 x 120mg tablets) daily
takes 1-3 days to work
can be used in pregnancy
oral bulking agents
useful if there is a dietary fibre deficiency
onset is usually by 24 hours, with peak action at 2-3 days following dosing
Ispaghula
1 sachet or teaspoon in water
Psyllium
as directed on packet, 1- 3 times a day
can be used in pregnancy
Sterculia
1–2 teaspoons 1–2/day
oral osmotic agents
lactulose
(Duphalac)
15-30ml once or twice a day
takes 1-2 days to work
can be used in pregnancy
other agents
oral stimulant laxatives
avoid long term use as they may induce melanosis coli, tolerance or cathartic colon and there is little evidence for their efficacy.
not proven to be safe in pregnancy
Bisacodyl
1–2 x 5 mg tablets daily
works in 6-12hrs
can be used in pregnancy
sennosides
works in 6-12hrs