allergy
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| allergy [2026/09/23 12:43] – [allergy and hypersensitivity reactions] gary1 | allergy [2026/09/23 12:43] (current) – [Introduction] gary1 | ||
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| *many people have allergies which may be to medicines, biological substances such as from bee stings, components in foods, contact substances or inhaled in the air | *many people have allergies which may be to medicines, biological substances such as from bee stings, components in foods, contact substances or inhaled in the air | ||
| *traditionally the various types of allergic reactions have been classified under the Gell and Coombs hypersensitivity reactions (see below) | *traditionally the various types of allergic reactions have been classified under the Gell and Coombs hypersensitivity reactions (see below) | ||
| - | *recently it has also been proposed that sensory nerves may " | + | *recently it has also been proposed that sensory nerves may " |
| * protease allergen exposure induced sustained mechanistic target of rapamycin complex 1 (mTORC1) kinase signaling and transcriptional activator peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α)-associated mitochondrial remodeling in sensory neurons, establishing a metabolically primed state with enhanced neuronal responsiveness. Upon allergen re-exposure, | * protease allergen exposure induced sustained mechanistic target of rapamycin complex 1 (mTORC1) kinase signaling and transcriptional activator peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α)-associated mitochondrial remodeling in sensory neurons, establishing a metabolically primed state with enhanced neuronal responsiveness. Upon allergen re-exposure, | ||
| =====Hypersensitivity reactions - the Gell & Coombs classification===== | =====Hypersensitivity reactions - the Gell & Coombs classification===== | ||
allergy.txt · Last modified: 2026/09/23 12:43 by gary1