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exercise [2026/04/01 04:11] – [Introduction] gary1exercise [2026/05/21 15:28] (current) – [research] wh
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       *a common null polymorphism in ACTN3 (R577X) arose in modern humans and underwent positive selection ~10 to 15,000 years ago       *a common null polymorphism in ACTN3 (R577X) arose in modern humans and underwent positive selection ~10 to 15,000 years ago
       *among the elderly, α-actinin-3 deficiency is associated with significantly lower strength and higher frailty scores in an elderly Chinese population       *among the elderly, α-actinin-3 deficiency is associated with significantly lower strength and higher frailty scores in an elderly Chinese population
 +  ***myokines**
 +    * cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by skeletal muscle cells (muscle fibers) in response to muscular contractions
 +    * receptors for myokines are found on muscle, fat, liver, pancreas, bone, heart, immune, and brain cells
 +    * they are involved in exercise-associated metabolic changes, as well as in the metabolic changes following training adaptation
 +    * they also participate in tissue regeneration and repair, maintenance of healthy bodily functioning, immunomodulation; and cell signaling, expression and differentiation
 +    * eg, myostatin, irisin
exercise.txt · Last modified: 2026/05/21 15:28 by wh

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