levetiracetam
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| levetiracetam [2026/01/30 03:45] – [iv administration] gary1 | levetiracetam [2026/01/30 03:51] (current) – [Introduction] gary1 | ||
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| *levetiracetam is a newer anticonvulsant with similar efficacy as [[phenytoin]] for status epilepticus but without the iv line incompatibility issues | *levetiracetam is a newer anticonvulsant with similar efficacy as [[phenytoin]] for status epilepticus but without the iv line incompatibility issues | ||
| *main mechanism involves binding to the synaptic vesicle protein 2A (SV2A), a key component of nerve cell vesicles, which modulates neurotransmitter release, potentially by inhibiting presynaptic calcium channels and reducing glutamate release, likely reducing excessive electrical signaling that causes seizures, without affecting normal brain activity | *main mechanism involves binding to the synaptic vesicle protein 2A (SV2A), a key component of nerve cell vesicles, which modulates neurotransmitter release, potentially by inhibiting presynaptic calcium channels and reducing glutamate release, likely reducing excessive electrical signaling that causes seizures, without affecting normal brain activity | ||
| + | *may also inhibit N-type calcium channel currents | ||
| *useful for: | *useful for: | ||
| * partial onset seizures (monotherapy) | * partial onset seizures (monotherapy) | ||
levetiracetam.txt · Last modified: 2026/01/30 03:51 by gary1