cmv
Table of Contents
cytomegalovirus (CMV)
introduction
- CMV is a member of the Herpesviridae family
- ~60% of western populations have been infected with CMV, most are asymptomatic, but it may become reactivated if T-cell immunity falls
primary CMV infection
- if symptomatic, incubation period is 9-60 days
- may cause:
- a flu-like illness with pharyngitis, perhaps mild pneumonitis with fine crackles
CMV infection in the immunocompromised
- may result in a mononucleosis syndrome and affect most organs in the body:
- rarely:
CMV reactivation
- CMV normally remains dormant but may become reactivated if T-ltmphocyte mediated immunity becomes compromised as in:
- immunosuppressants such as azathioprine Rx
- CMV viraemia may then lead to:
- severe pneumonitis
- secondary haemophagocytic syndrome
cmv.txt · Last modified: 2014/06/02 11:17 by 127.0.0.1