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dm_1stdxmx

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Mx of 1st presentation diabetes mellitus

Introduction

  • this is a brief outline of initial ED Mx of an adult patient found to have a high blood glucose

Initial Ix in ED of adults

  • usual ABC's of ED - move to resus if critically unwell
  • take bloods for glucose, FBE, U&E, osmolarity, and if raised ketones > 1mmol/L on bed side testing, do blood gases
  • look for precipitants
    • bloods, etc for septic workup as indicated
    • in older adults check for acute coronary syndrome
  • clinical history and exam as usual
    • is their FH?
    • Hx of hyperglycaemic symptoms of polyuria, polydipsia, etc
    • BMI

ketotic patient

non-ketotic patient

hyperosmolar state

  • IV fluid rehydration and insulin Rx as per your hospital's procedures

normal osmolarity

  • discuss with endocrine team for a plan which may include:
    • serum HbA1c (NB. may be artificially low in those with G6PD)
    • TFTs
    • fasting lipids
    • fasting C-peptide
    • fasting glucose
    • additional auto-antibody tests
      • zinc transport 8 antibodies
      • anti gliadin antibodies
      • tissue transglutaminase antibodies
      • anti glutamic acid decarboxylase antibodies
      • insuloma antigen (IA2) antibodies
    • start basal bolus insulin
      • eg. glargine insulin 14 units nocte if normal BMI
    • initial tds short acting insulin
      • eg. aspart insulin 4 units tds if normal BMI
    • observe until glucose under control then pending results consider changing to oral agents
dm_1stdxmx.1759280543.txt.gz · Last modified: 2025/10/01 01:02 by gary1

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