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spine_calcification

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abnormal calcifications of the spine

Introduction

Ossification of the posterior longitudinal ligament (OPLL)

  • a hyperostotic condition that results in ectopic calcification of the posterior longitudinal ligament
  • most common in those from East Asia backgrounds
  • four subtypes:
    • continuous
    • segmental
    • mixed
    • localized or other

aetiology

  • genetic factors
    • familial inheritance (genes including BMP4, BMP9, and COL6A1) has been associated with the development of OPLL

Mx

  • conservative unless develops neurologic symptoms in which case will need neurosurgical Mx

Ossification of the anterior longitudinal ligament (OALL)

  • often seen with Diffuse Idiopathic Skeletal Hyperostosis (DISH) (aka Forestier’s disease)
  • mostly observed in the elderly
  • large cervical ossifications can make endotracheal intubation extremely difficult during anesthesia; specialized awake fiberoptic intubation techniques are often planned

Mx

  • gentle stretching and ROM exercises to maintain mobility of spine
  • surgery is reserved for rare cases with severe complications such as progressive dysphagia, severe dyspnea, or airway obstruction
spine_calcification.1786274125.txt.gz · Last modified: 2026/08/09 11:15 by wh

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