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leukaemia

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leukaemia [2026/05/10 20:02] – [chronic lymphocytic leukaemia (CLL)] whleukaemia [2026/05/10 20:03] (current) – [chronic lymphocytic leukaemia (CLL)] wh
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   *mainly occurs in adults aged 55yrs and over, with 2/3rds in men   *mainly occurs in adults aged 55yrs and over, with 2/3rds in men
   *almost never occurs in children   *almost never occurs in children
-  *up to 5% have POT1 mutation which increases risk of CLL 16-fold and is also associated with 7-fold risk of melanomas, and high risk of lymphomas, [[sarcoma|sarcomas]] (([[https://ashpublications.org/blood/article/147/19/2226/566170/Lymphoid-malignancy-and-clonality-in-the-POT1|2026: Lymphoid malignancy and clonality in the POT1-mediated long telomere syndrome ]]))+  *up to 5% have [[POT1_mutation|POT1 mutation]] which increases risk of CLL 16-fold and is also associated with 7-fold risk of melanomas, and high risk of lymphomas, [[sarcoma|sarcomas]] (([[https://ashpublications.org/blood/article/147/19/2226/566170/Lymphoid-malignancy-and-clonality-in-the-POT1|2026: Lymphoid malignancy and clonality in the POT1-mediated long telomere syndrome ]]))
   *5yr survival 75%   *5yr survival 75%
  
leukaemia.txt · Last modified: 2026/05/10 20:03 by wh

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