endo_chemicals
Table of Contents
endocrine disrupting chemicals (EDCs)
see also:
Introduction
- endocrine disrupting chemicals (EDCs) are chemicals which can mimic, block, or interfere with the body's hormones
- 95% of people have endocrine disrupting chemicals in their body
- there are over 800 chemicals recognised or suspected of being EDCs
- xenoestrogens (XE) include as parabens and phthalates which are commonly used in personal care products (PCPs) and which may increase the risk of breast cancer 1)
Pathophysiology
- may mimic, block, or interfere with the body's hormones
- may activate pregnane X receptor (PXR) (a major regulator of drug metabolism) which then increases SHBG levels and total testosterone levels2)
Sources of EDCs
-
- in plastic containers, especially squeezy plastic bottles
- avoid putting food in these containers into a microwave especially fatty foods which tend to absorb chemicals
- avoid personal care products (PCPs) containing these
- bisphenols (Bisphenol A (BPA), etc) such as bisphenol A (BPA)
- chemicals used in the lining of some food and beverage packaging to protect food from contamination and extend shelf life
- in addition to its endocrine effects, during fetal development, the combination of BPA and retinoic acid (RA) appears to trigger abnormal brain and facial development by overstimulating RA-responsive genes, particularly a group known as HOX genes 4)
- BPA is now removed from many plastics but “BPA-free” may just mean they have been substituted with inadequately researched substances - often another BPA-like one
- concerns have been raised that some BPA substitutes may also cause adverse effects such as on the ovary5)
- dioxins
- can be released from plastics which are reheated and then can be absorbed into food
- other examples:
- oily fish like tuna, sardines, for example, they can absorb a lot of those chemicals from their environment
- tinned food is often lined with plastics
- herbicides and pesticides sprayed onto fruit and vegetables
Minimising your exposure
- don't put plastic containers into the microwave
- avoid re-using plastic bottles
- transfer foods from plastic to china or stainless steel as soon as possible
- minimise tinned foods with plastic seals inside
- minimise oily fish intakes
- wash fruit and vegetables
- avoid handling paper receipts, especially with wet hands and don't keep them in your wallet
- avoid personal care products (PCPs) containing these chemicals
endo_chemicals.txt · Last modified: 2026/04/01 00:46 by gary1