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ovhss

ovarian hyperstimulation syndrome (OHSS)

see also:

Introduction

  • a complication of IVF therapies which although most cases are mild, can result in severe illness and generally lasts 1-2 weeks

Clinical features

mild OHSS

  • ovarian enlargement to 5-12cm
  • ascites with mild abdominal distension
  • abdominal pain
  • nausea
  • diarrhoea

severe OHSS

  • additional features may include:
    • ascites
    • hematocrit > 45%
    • WBC > 15,000
    • oliguria
    • creatinine 1.0-1.5 mg/dl
    • creatinine clearance > 50 ml/min
    • liver dysfunction
    • anasarca.

critical OHSS

  • may include:
    • enlarged ovary
    • tense ascites with hydrothorax and pericardial effusion
    • hematocrit > 55%
    • WBC > 25,000
    • oligoanuria,
    • creatinine > 1.6 mg/dl
    • creatinine clearance < 50 ml/min
    • kidney failure
    • thromboembolic phenomena
    • ARDS

Complications

  • may be complicated by:
    • ovarian torsion
    • ovarian rupture
    • venous thromboembolism
    • acute respiratory distress syndrome
    • electrolytes imbalance
    • thrombophlebitis
    • chronic kidney disease
ovhss.txt · Last modified: 2022/12/04 01:07 by wh

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