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p-cabs

potassium-competitive acid blockers (P-CABs)

Introduction

  • potassium-competitive acid blockers (P-CABs) are a class of medications which suppress gastric acid secretion apparently with more rapid and consistent acid suppression, negligible CYP2C19 interaction, longer half-life, and high tolerability than with proton pump inhibitors (PPIs)
  • they competitively bind the potassium-binding sites in proton pumps

Examples

  • vonoprazan
  • revaprazan
  • tegoprazan
  • fexuprazan
p-cabs.txt · Last modified: 2026/08/26 12:12 by gary1

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