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sarcopenia / generalised muscle wasting


  • sarcopenia is a very common problem with aging and is a leading cause of frailty
  • it is characterized by progressive and generalized loss of skeletal muscle mass and strength
  • it has high correlations with physical disability, poor quality of life and death
  • presarcopenia stage is characterized by low muscle mass without impact on muscle strength or physical performance
  • loss in muscle mass may be associated with increased body fat so that despite normal weight there is marked weakness, this is a condition called sarcopenic obesity.
  • sarcopenia is different to cachexia which may be defined as a multifactorial syndrome characterized by severe body weight, fat and muscle loss and increased protein catabolism due to underlying disease


  • primarily a syndrome of old age
  • risk factors include:
    • age
    • gender
    • low level of physical activity
    • protein malnutrition
    • chronic inflammatory conditions
sarcopenia.txt · Last modified: 2020/05/21 21:07 by gary1