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spinal_stenosis

spinal stenosis

Introduction

  • spinal stenosis is narrowing of the spinal canal or neural foraminae resulting in pressure on the spinal cord or nerve roots
  • “central stenosis” is used if the whole central spinal canal is compressed, and “foraminal or lateral stenosis” if the single nerve root exiting the neural foramina is compressed
  • lumbar stenosis is most common followed by cervical stenosis
  • 1st described by Antoine Portal in 1803

Lumbar spinal stenosis (LSS)

Aetiology

  • usually degenerative as a result of lumbar facet joint degenerative arthropathy and thus occurs mainly in those over 50yrs age and females are at higher risk
    • as the disks dry out with age and lose height, more weight is taken on by the facet joints leading to arthritic changes and the neural foraminae become smaller
    • affects some 8% of the elderly population
  • congenital forms may present between ages 30 and 50 yrs
    • congenitally small central canal
  • genetic factors
    • heritability of LSS appears to be 0.67
    • over 88 genetic regions are associated1)
    • at least 32 genetic regions are associated to more advanced forms of the disease requiring surgical treatment
    • most variants influence risk after midlife, but some confer susceptibility as early as age 34
  • other causes include rheumatoid arthritis, ankylosing spondylitis (AS), spinal tumours, trauma, Paget's disease, scoliosis, spondylolisthesis, achondroplasia
  • whole body fat-free mass and higher LSS risk (OR = 1.724)2)
  • body mass index (BMI) and higher LSS risk (OR = 1.553)3)

Epidemiology

  • affects over 100 million people globally, with an increasing incidence due to an ageing population
  • prevalence of diagnostic LSS is around 11%, increasing significantly with age - the majority of radiological LSS cases are asymptomatic
  • majority of diagnoses occurring between the ages of 50 and 70

Clinical features

  • low back pain can be present or absent
  • pain on standing
  • symptoms are typically relieved during sitting or forward flexion
  • neurogenic intermittent claudication may occur on prolonged standing, walking or extension of the lumbar spine
  • sciatica may occur and may be bilateral
  • severe cases may cause cauda equina syndrome (CES)

Diagnosis

  • MRI or CT scan

Management

  • analgesia
  • activity modification
  • physiotherapy
  • surgical Rx may be needed if:

Cervical spinal stenosis

spinal_stenosis.txt · Last modified: 2026/06/10 03:46 by gary1

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