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yellow fever


  • occurs in urban and rural areas of Africa and central South America
  • caused by a mosquito-borne flavivirus
  • monkeys are the main reservoir but mosquitoes can spread it from human to human
  • the highest risk for YFV transmission is during the day and early evening
  • a vaccine to prevent it is available

clinical features

  • most are asymptomatic

symptomatic phase I

  • fever, muscular pain, headache, chills, anorexia, nausea and/or vomiting, often with bradycardia

symptomatic phase II

  • 15% of patients progress to a second phase after a few days
  • resurgence of fever, development of jaundice, abdominal pain, vomiting and haemorrhagic manifestations
  • up to half of these patients die 10–14 days after the onset of illness
yellow_fever.txt · Last modified: 2013/12/31 03:19 by gary1