see also:

• pathology

• ENA is a blood test looking for extractable nuclear antigens which are >100 different soluble cytoplasmic and nuclear antigens.
• autoantibodies to these antigens are associated with particular connective tissue (CT) disorders:
  • anti-Sm (for systemic lupus erythematosus (SLE))
  • anti-RNP (for MCTD)
  • anti-La (for Sjögren's syndrome)
  • anti-Ro (for Sjögren's syndrome)
  • anti-Scl70 (for scleroderma)
  • anti-Jo (for dermatomyositis)