avoid prolonged courses, particularly in the elderly as risk of cholestatic jaundice, consider dicloxacillin instead as risk is half that for flucloxacillin
- flucloxacillin is a narrow spectrum penicillin active against Gram +ves including St. aureus
- not active against Gram negative bacilli, methicillin resistant Staphylococcus, nor Streptococcus faecalis.
- category B1 in pregnancy
- is excreted in breast milk in trace amounts. An alternative feeding method is recommended to avoid any possible sensitisation of the newborn.
- HS reaction including anaphylaxis
- cholestatic jaundice - usually after several weeks of Rx
- reduces binding of bilirubin to albumin thus avoid in jaundiced neonates or premature neonates
- sodium load in renally impaired patients - each 1g flucloxacillin contains 2mmol sodium
- adults 500mg qid
- children 2-10 years 250mg qid
- children < 2yrs: 125mg qid
- adult dose 500mg - 1g 6hrly
- children 2-10 years 250-500mg qid
- children < 2yrs: 125-250mg qid
flucloxacillin.txt · Last modified: 2012/01/09 03:59 by 127.0.0.1