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laxatives

laxatives

see also:

Introduction

oral stool softeners

  • docusate
    • 240mg (2 x 120mg tablets) daily
    • takes 1-3 days to work
    • can be used in pregnancy

oral bulking agents

  • useful if there is a dietary fibre deficiency
  • onset is usually by 24 hours, with peak action at 2-3 days following dosing
  • Ispaghula
    • 1 sachet or teaspoon in water
  • Psyllium
    • as directed on packet, 1- 3 times a day
    • can be used in pregnancy
  • Sterculia
    • 1–2 teaspoons 1–2/day

oral osmotic agents

  • lactulose (Duphalac)
    • 15-30ml once or twice a day
    • takes 1-2 days to work
    • can be used in pregnancy
  • other agents

oral stimulant laxatives

  • avoid long term use as they may induce melanosis coli, tolerance or cathartic colon and there is little evidence for their efficacy.
  • not proven to be safe in pregnancy
  • Bisacodyl
    • 1–2 x 5 mg tablets daily
    • works in 6-12hrs
    • can be used in pregnancy
  • sennosides
    • works in 6-12hrs
laxatives.txt · Last modified: 2019/06/27 13:28 (external edit)