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neo_vulval

vulval cancer

introduction

  • like cervical cancer, vulval carcinoma is associated with human papilloma virus (HPV) infection
  • striking increase in vulval intraepithelial neoplasia (VIN) since 1980 with the median age of presentation falling to the mid-30's
    • at least 2/3rds of these women smoke cigarettes
    • nearly 50% have PH of SIL/CIN
    • many of the younger women have HPV DNA on biopsy

clinical presentations

  • vulvar pruritus
  • vulval lump
  • warty vulvar lesion which may be unifocal or multifocal, flat, papular or in extensive plaques, pigmented, white or red
  • transit times from VIN III to invasion is less than 8yrs in nearly all studies, thus any gross lesion should be biopsied or referred to a vulvar specialist
neo_vulval.txt · Last modified: 2009/10/30 09:37 (external edit)