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orbital_cellulitis

Periorbital and orbital cellulitis

Introduction

  • periorbital (“preseptal”) cellulitis is superficial and does not extend deep to the orbital septum but may do so in which case it becomes orbital cellulitis
  • orbital cellulitis extends deep to the orbital septum and risks permanent eye damage, intracranial infection and sepsis
  • infection is generally either local spread from soft tissues or sinuses, but may be systemically spread with seeding from bacteraemia / septicaemia eg. H. influenzae type b (HiB)
    • HiB vaccination of children since the early 1990s has practically eradicated life-threatening childhood invasive HiB infection such as orbital cellulitis, meningitis, septicaemia and epiglottitis
  • usual pathogens are Staph. aureus, Strept, H. influenzae type b (HiB), anaerobes, and in immunocompromised or diabetics, fungi may be the cause
  • orbital cellulitis is a rare emergency with risk of septic shock, intracranial spread (brain abscess or meningitis) and ocular damage and thus needs to be explicitly differentiated from periorbital cellulitis
    • features suggestive of orbital cellulitis rather than just periorbital cellulitis include:
      • children aged under 4yrs are at particular risk, especially if not vaccinated for H. influenzae type b (HiB)
      • immunocompromised patients
      • systemically unwell
      • fever
      • chemosis
      • proptosis
      • diplopia
      • painful eye movements
      • impaired visual acuity or visual fields
      • presence of a more likely aetiology such as:
        • orbital trauma
        • post-op
        • foreign body in orbit
      • NB. examination of the eye may be very difficult due to extreme swelling but should be pursued or CT scan performed if examination cannot exclude orbital cellulitis
      • NB. both periorbital and orbital cellulitis may be due to odontogenic sinusitis, dacrocystitis, or local infection but patients with periorbital cellulitis alone tend to be afebrile without eye signs or fever
    • necrotising fasciitis of the face is extremely rare
      • here is a case: necrotising fasciitis from an otherwise innocuous minor cut 1)

Mx of periorbital cellulitis in adults

  • those who are at low risk for HiB infection without concurrent sinusitis are generally covered for Staph. aureus
  • those with sinusitis or at risk of HiB are generally Rx with broad spectrum antibiotics - see your local guidelines
  • patients should be reviewed in 24hrs for response to Rx and exclusion of signs of orbital cellulitis

Mx of orbital cellulitis

  • blood cultures
  • usual bloods
  • if septic, start IV antibiotics ASAP (preferably within 1 hr)
    • eg. ceftriaxone + flucloxacillin (use vancomycin instead if MRSA risk) - see your local guidelines
  • resuscitate as usual if septic shock
  • urgent CT scan orbits and sinuses +/- CT brain if brain abscess is suspected
  • 4hrly eye obs - acuity and pupillary reaction
  • may require urgent surgical drainage to avoid permanent visual loss

DDx

  • need to distinguish cellulitis from:
    • allergic reaction - usually bilateral and non-tender to light touch
    • gravitational oedema / bruise from a forehead injury
    • dermatological rashes
orbital_cellulitis.txt · Last modified: 2025/10/08 07:52 by gary1

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