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risk factors for invasive pneumococcal disease

category A - highest risk

  • functional or anatomic asplenia such as splenectomy, sickle cell disease (SCD) or other haemoglobinopathies
  • immunocompromise:
    • symptomatic IgG sublass or isolated IgA deficiency
    • immunosuppressive Rx such as high dose corticosteroids for more than 1wk or radiation Rx
    • haematologic and other malignancies
    • solid organ transplant
    • haemopoietic stem cell transplant
    • [CRF]] or relapsing or persistent nephrotic syndrome
  • proven or presumptive CSF leak
  • cochlear implants
  • intracranial shunts

category B - medium risk

  • chronic cardiac disease (excluding isolated adult hypertension), particularly paediatric
  • chronic lung disease including preterm infants, cystic_fibrosis and severe asthma requiring frequent hospital visits or multiple medications
  • diabetes
  • Down's syndrome
  • alcoholism
  • chronic liver disease
  • preterm birth < 28wks gestation (should be vaccinated to age 5yrs)
  • tobacco smoking

prophylactic vaccination

pneumococcus.txt · Last modified: 2014/01/13 05:49 by

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