- it's use is usually restricted to seronegative spondyloarthropathy which restricts it to a group of inflammatory conditions usually associated with HLA-B27 and which have a negative anti-nuclear antibodies (ANA) and RhF.
- these conditions often cause:
- spondylitis (inflammation of the spine)
- asymmetric peripheral arthritis (which is distinct from rheumatoid arthritis)
- arthritis of the toe IP Joints
- sausage digits
- enthesitis such as achilles tenosynovitis
- plantar fasciitis
- iritis / uveitis
- mucocutaneous lesions including genital lesions
- enteropathic spondylitis (spondylitis associated with inflammatory bowel disease (IBD))
- psoriatic arthritis
- ~20% develop spondylitis +/- sacroiliitis
- most have onychodystrophy
- proximal interphalangeal joints and distal interphalangeal joints are commonly involved with characteristic sausage-shaped digits.
- knees, hips, ankles, temporomandibular joints, and wrists are less frequently involved.
- 25% develop a symmetric arthritis similar to rheumatoid arthritis
- isolated acute anterior uveitis
- Undifferentiated spondyloarthropathy (USpA)
spondyloarthopathies.txt · Last modified: 2018/07/17 13:37 by 127.0.0.1