androgenetic alopecia is male pattern balding which appears to have a multi-factorial causation although genetic polymorphisms appear to have a key role which may influence the hair follicle cycle and the drivers of this cycle such as androgens
, and insulin-like growth factors (IGFs)
30% of men developed androgenetic alopecia by the age of 30 and 50% by the age of 50
the three key features of androgenetic alopecia pathogenesis are:
eunuchs, patients with androgen-insensitivity syndrome and those with 5α-reductase deficiency do NOT go bald in this manner, suggests that androgenetic alopecia is induced by activation of follicular androgen receptors by dihydrotestosterone.
there are possible associations with other conditions such as:
alopecia_androgenetic.txt · Last modified: 2019/07/13 16:46 by wh