nitrous_oxide

nitrous oxide

Introduction

  • a commonly used anesthetic, inhaled analgesic agent
  • also readily available to the public as used to inflate balloons and in whipping cream and thus is subject to chronic abuse
  • commonly abused in the form of nangs which are small canisters of nitrous oxide designed to make cream fluffy and long-lasting
    • inhaled on its own it can give the recreational user an incredibly short 20second but intense high
    • there is no “comedown”, as there is with most party drugs and user is usually back to normal self within minutes
    • along with MDMA, they are the drug of choice for schoolies week, due to the fact that they’re not only cheap, but available at every corner store
    • long-term use has been associated with functional vitamin B12 deficiency resulting in peripheral neuropathy, spinal degeneration and potentially CNS effects such as paranoia, delusions, hallucinations and behavioural changes 1)

Acute toxicity

  • nitrous oxide gas is very cold (-40C degrees) and can cause frostbite to the nose, lips and throat (including vocal cords)
  • faulty gas dispensers can cause harm as they may explode
  • nausea, vomiting
  • dizziness
  • euphoria
  • CNS depression
  • syncope
  • seizures

Chronic abuse

  • may lead to:
    • bone marrow suppression and impaired immune system
    • nitrous oxide neurotoxicity
      • memory loss
      • vitamin B12 depletion and neuropathies
        • the B12 impaired metabolism can result in neurologic and psychiatric symptoms which can, in turn, reinforce nitrous oxide use
        • may present with unsteady gait, leg weakness and paraesthesiae due to functional B12 deficiency dorsal column neuropathy
      • tinnitus
    • depression
    • psychological dependence
    • psychosis
nitrous_oxide.txt · Last modified: 2026/01/24 22:11 by wh

Donate Powered by PHP Valid HTML5 Valid CSS Driven by DokuWiki