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polymyositis

polymyositis (PM)

introduction

clinical features

  • often present with painful and marked weakness and/or loss of muscle mass in the proximal musculature, particularly in the shoulder and pelvic girdle (see weakness of the lower limb(s) / weak in the knees)
  • hip extensors are often severely affected, leading to particular difficulty in ascending stairs and rising from a seated position
  • weakness is generally progressive, accompanied by lymphocytic inflammation (mainly cytotoxic T lymphocytes)
  • sclerodactyly, dysphagia or interstitial lung disease may occur

diagnosis

Mx

polymyositis.txt · Last modified: 2013/09/27 06:33 by gary1