immunosuppressants
immunosuppressants
classes of immunosuppressant medications
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topical immune modifiers:
selective interleukin inhibitors:
selective tumour necrosis factor (TNF) inhibitors:
interferons:
interferon alpha-2b: Rx of hairy cell leukaemia, Kaposi's sarcoma, chronic hepatitis B/C, CML, multiple myeloma, non-Hodgkin's lymphoma, melanoma, etc
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interferon gamma-1b: reduces infections in chronic granulomatous disease
other transplant rejection prevention agents:
mycophenolate mofetil - renal allograft rejection in children
everolimus - mTOR inhibitor also used to Rx AD polycystic kidney disease (ADPKD)
sirolimus
tacrolimus - macrolide lactone immunosuppressant used as adjunctive Rx
antithymocyte globulin - to reduce peripheral T cell function in renal transplant recipients
basiliximab - renal allografts
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immune modulators for Rx of asthma:
omalizumab - anti-IgE agent which appears to reduce seasonal peaks in exacerbations in inner city children with asthma
1)
lenalidomide - for Rx of multiple myeloma and transfusion dependent anaemia
thalidomide - for Rx of multiple myeloma
temsirolimus - Rx of advanced renal cell Ca, and relapsed, refractory mantle cell lymphoma
immunosuppressants.txt · Last modified: 2020/04/02 12:37 by gary1