Severe fever with thrombocytopenia syndrome virus (SFTSV)

introduction

an emerging infectious zoonosis in China, Japan, and South Korea
newly identified tick-borne bunyavirus (of genus Phlebovirus) discovered in 2007
similar to viral haemorrhagic fevers
case fatality rate ~15%
incubation period up to 3 weeks
1 week prodrome of fever, headache, myalgia, arthralgia, dizziness, and malaise
clinical features following prodrome:
- mucosal haemorrhage
- haemorrhagic rash
- thrombocytopenia
- elevated liver enzymes
- multi-organ failure
- disseminated intravascular coagulopathy (DIC)
- confusion