siadh
syndrome of inappropriate ADH secretion (SIADH)
introduction
SIADH is increased ADH secretion despite normal or elevated plasma volume which causes reduced renal water excretion and resulting
hyponatraemia and hypo-osmolality
aetiology
central nervous system causes
brain tumours
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encephalopathies
brain abscess
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hydrocephalus
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etc…
drug-induced
increased secretion of ADH
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nicotine
histamine
acetylcholine
bromocryptine
antineoplastic agents
chlorpropamide
halothane
nitrous oxide
increased effects of ADH
other drugs include
pulmonary causes
paraneoplastic
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Ewing sarcoma
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nasopharyngeal tumours
thymoma
adrenocortical carcinoma
olfactory neuroblastoma
ectopic ADH secretion
other causes
Mx
siadh.txt · Last modified: 2014/03/11 19:07 (external edit)