rash_generalised

acute generalized non-vesicular non-purpuric rashes covering most parts of the body

DDx

acute rash with mucosal involvement

those involving palms

  • urticaria
  • erythema multiforme
  • drug eruption
  • Kawasaki disease
  • Toxic shock syndrome
  • HIV seroconversion
  • gonococcal
  • secondary syphilis
  • rubella
  • scabies (in infants)
  • Tinea corporis
  • psoriasis

asymmetric generalised rashes

  • urticaria
  • meningococcal
  • sepsis
  • scabies

symmetric generalised rashes starting from head downwards

  • measles (starts behind ears or on forehead at hairline)
  • fifth disease (starts as slapped cheeks)
  • rubella - facial rash usually clears as it spreads to other parts of the body
  • scarlet fever - rash usually starts below the ears, neck, chest, armpits and groin before spreading to the rest of the body over 24 hours.

symmetric generalised rashes starting from trunk downwards

  • morbilliform drug eruption
    • usually appears 1–2 weeks after starting the drug, but it may occur up to 1 week after stopping it
    • usually first appears on the trunk and then spreads to the limbs and neck
  • many non-specific paediatric exanthems
  • secondary syphilis - mainly trunk and extremities including palms and soles 4-10wks after primary infection

symmetric rashes starting on trunk then going to face and arms

mainly on trunk only

  • roseola - rarely spreads to involve the neck, face, arms and legs
  • pityriasis rosea
    • herald patch on trunk usually; secondary plaques appear on trunk most often appearing from the top down, a few plaques may also appear on the thighs, upper arms, and neck, but are uncommon on the face, scalp, palms, or soles
    • mainly affects hot sweaty areas covered by clothing
  • Grover disease (transient acantholytic dermatosis)
    • pruritic rash most often affects Caucasian men over 50 years of age with sundamaged skin and may involve upper arms

symmetric rashes starting from lower legs and going proximally

  • hand foot and mouth - purplish vesicular lesions on fingers/toes then may get m/p rash on buttocks and mouth lesions
  • erythema multiforme - these may be mac/pap in early stage
  • mycoplasma - these may be mac/pap in early stage
rash_generalised.txt · Last modified: 2026/04/16 23:05 by gary1

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