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cytotoxics

cytotoxic agents

alkylating agents

  • alkylating agents (damage DNA classically by adding an alkyl group):
    • nitrogen mustards such as:
      • cyclophosphamide
      • melphalan
      • chlorambucil
      • ifosfamide
      • bendamustine
        • introduced Aust. PBS 2014 for Rx CLL and non-Hodgkin lymphoma
    • nitrosoureas such as:
      • carmustine
      • lomustine
      • streptozocin
    • alkyl sulfonates such as:
      • busulfan
    • platinum agents such as cis-platinum

antimetabolites

  • azathrioprine - prodrug for mercaptopurine
  • cytarabine - a pyrimidine analogue used to Rx AML
  • bleomycin
  • dactinomycin / actinomycin D
  • mitomycin
  • hydroxyurea
  • mercaptopurine
  • thioguanine

anthracycline agents

  • doxorubicin
  • epirubicin
  • mitozantrone
  • idarubicin

podophyllotoxins

  • etoposide

vinca alkaloids

  • vinorelbine
cytotoxics.txt · Last modified: 2014/12/16 15:38 (external edit)