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splenomegaly

splenomegaly

introduction

  • craniocaudal measurement of 11-13 cm is frequently used as the upper limit of normal splenic size on imaging studies
  • 2-5% of the population have a palpable spleen
  • patients with splenomegaly should be advised to avoid all contact sports as there is a risk of fatal splenic rupture
  • splenic rupture risk is higher in older patients as the splenic capsule thins with age

hypersplenism

  • criteria include:
    • anemia, leukopenia, thrombocytopenia, or combinations thereof, plus,
      • cellular bone marrow
      • splenomegaly
      • improvement after splenectomy
  • chronic, severe hypersplenism may occur in:
    • hairy cell leukaemia
    • Felty syndrome
    • agnogenic myeloid metaplasia
    • thalassemia major
    • Gaucher disease
    • haemodialysis splenomegaly
    • splenic vein thrombosis

aetiology

splenomegaly.txt · Last modified: 2013/04/07 12:25 (external edit)