hand, foot and mouth disease (mainly children, causes purplish blisters as well as fevers, malaise)
juvenile palmar-plantar dermatosis “sweaty-sock syndrome” (mainly toddlers, school-aged children)
atopic dermatitis (may cause chronic hand and foot dermatitis)
secondary syphilis (multiple red lesions on palms and soles)
erythema multiforme (may present as target lesions mainly on palms)
gononoccoccal (rarely can cause small, painful, red spots or pustules mainly of palms and soles)
palmoplantar pustulosis (PPP) / pustular psoriasis (rare, recurrent/chronic red scaly / pustular rash)
contact dermatitis
dyshidrotic eczema (causing small, itchy blisters)
hand-foot syndrome (a chemotherapy side effect causing redness and swelling)
tinea pedia / tinea mannuum
acute cutaneous lupus erythematosus
adult-onset Still's disease
palmar erythema / plantar erythema (non-painful red warm skin mainly proximal palms and heels)